The Science
The research
behind ONE.
Every ingredient is in the formula for a reason. Here's the science.
Hydration
Why water alone isn't enough.
Water is essential. But it's only half the equation.
Your cells are surrounded by fluid that needs to maintain a precise balance of electrolytes — sodium, potassium, and magnesium — to function properly. Without these minerals, water can't cross the cell membrane efficiently. It moves through your system without fully hydrating you.
This is why you can drink eight glasses of water a day and still feel fatigued, foggy, or cramped. The water is there. The minerals aren't.
75% of Americans are chronically dehydrated — not because they aren't drinking enough water, but because they're missing the electrolytes that make hydration work.
ONE replaces what water can't provide.
Sodium
Regulates fluid balance outside your cells. Without it, water can't be retained — no matter how much you drink.
Potassium
Works with sodium to move fluid inside your cells. The two must be in balance for proper cellular hydration.
Magnesium L-Threonate
Supports the cellular processes that make hydration possible — and the only form that also crosses the blood-brain barrier.
Source: NIH, Nutrition Reviews (2010)
The Problem
75% of Americans are chronically dehydrated.
Most people reach for water. But water alone isn't enough. Without electrolytes, your cells can't absorb and retain fluid properly. The result — fatigue, brain fog, muscle cramps, and reduced performance — even when you're drinking plenty. Dehydration isn't always thirst. Most of the time, you don't feel it until it's already affecting you.
Source: NIH, Nutrition Reviews (2010)
The Solution
Science-backed hydration — at the cellular level.
ONE is built around three clinically studied ingredients. Each one is included at a meaningful dose, for a specific reason. No filler. No padding the label.
Key Ingredients
Himalayan Mineral Salt
Fluid balance + thermoregulation
500 mg Sodium
Sodium is the primary electrolyte responsible for fluid balance outside your cells. Without adequate sodium, your body struggles to retain water — no matter how much you drink. Himalayan salt provides sodium alongside naturally occurring trace minerals stripped out of standard table salt. Studies confirm sodium supplementation during exercise reduces performance decrements and supports thermoregulation.
Source: Shirreffs & Sawka, Journal of Sports Sciences (2011)
Potassium Chloride
Muscle function + nerve signaling
200 mg Potassium
Potassium works in tandem with sodium to regulate fluid inside and outside your cells. It supports muscle contraction, nerve signal transmission, and healthy heart rhythm. Low potassium is directly linked to cramping, weakness, and fatigue — particularly during prolonged physical activity.
Source: Houston, Journal of Clinical Hypertension (2011)
Magnesium L-Threonate (Magtein®)
Focus + memory + mental clarity
72 mg Magnesium
Most electrolytes use magnesium oxide or citrate — forms with poor bioavailability that barely reach the brain. ONE uses Magtein® — a patented form of magnesium developed by scientists at MIT. It is the only form of magnesium clinically demonstrated to cross the blood-brain barrier, measurably increasing magnesium levels in the brain. Clinical trials show Magtein® supports memory, focus, learning, and mental clarity. For ONE, this is the difference between a product that hydrates your body and one that sharpens your mind at the same time.
Source: Liu et al., Neuron (2010) — MIT. Slutsky et al., Journal of Alzheimer's Disease (2016)
Flavor
Flavor from fruit. Nothing else.
Most brands use "natural flavors" — a legal catchall that can include carrier oils, solvents, and fillers you'd never knowingly consume. ONE uses only organic dried fruit for flavor. No natural flavor concentrate. No carrier oil. No filler. Just the fruit, dried and ground — the way it was before food manufacturing got complicated.
What We Left Out
What we left out.
01
No added sugar
Zero grams of added sugar. Ever.
02
No artificial sweeteners
No sucralose, aspartame, or acesulfame potassium.
03
No artificial colors or dyes
No Red 40, no Blue 1, no synthetic colorants of any kind.
04
No natural flavor concentrates
No 'natural flavor' catchall. Flavor comes from real organic dried fruit.
05
No carrier oils or fillers
No maltodextrin, no silica, no gums, no anti-caking agents.
06
No gluten, no dairy
Gluten-free and dairy-free by formulation.
07
Non-GMO
Sourced from non-GMO suppliers, verified at every step.
08
Vegan
No animal-derived ingredients anywhere in the formula.
Magnesium
Why the magnesium form matters.
Not all magnesium is created equal. The form of magnesium in your electrolyte determines whether it actually reaches your brain — or gets stopped at the door.
Most brands use magnesium oxide (cheapest, lowest absorption) or magnesium malate (better, but no brain access). Neither crosses the blood-brain barrier. That means your body may absorb some magnesium, but your brain gets none of it.
ONE uses Magtein® — Magnesium L-Threonate. Developed at MIT. The only form clinically shown to cross the blood-brain barrier and measurably increase magnesium levels in the brain.
Magnesium form by brand.
ONE
Form: Magnesium L-Threonate (Magtein®)
Brain absorption: Yes — crosses blood-brain barrier
LMNT
Form: Magnesium Malate
Brain absorption: No
Nuun Sport
Form: Magnesium Oxide
Brain absorption: No — lowest bioavailability
Liquid IV
Form: None
Brain absorption: —
What's in the flavor.
Most brands use "natural flavors" — a legal umbrella term that can include carrier oils, solvents, and processing agents that never appear on the label. ONE uses only organic dried fruit. Nothing hidden behind a catchall term.
ONE
Flavoring: Organic dried fruit
Transparent: Yes — fully disclosed
LMNT
Flavoring: "Natural Flavors"
Transparent: No
Liquid IV
Flavoring: "Natural Flavors"
Transparent: No
Nuun
Flavoring: "Natural Flavors"
Transparent: No
Ingredient data sourced from published product labels. Accurate as of 2026.
Purity Standards
Clean sourcing. Full transparency.
Every ingredient in ONE is sourced from verified suppliers and held to strict quality standards. We publish exactly what is in the formula — nothing hidden behind proprietary blends or vague ingredient names. What you see on the label is what is in the pack.